"It has been 10 years since the Pandora Box was discovered on Mars and caused the Sky Wall tragedy. Our country was divided into Touto, Seito, and Hokuto, resulting in untold chaos."
"It has been 10 years since the Sky Wall tragedy. In the attempt to open the Pandora Box and release its massive amount of energy capable of destroying the world...a new battle has begun."
"The Pandora Box, which contains enough energy capable to destroy the Earth, has finally been opened. The alien lifeform Evolto controls that power...but the Kamen Riders stand against him!"
10 years ago, the Pandora Box was discovered on the planet Mars and brought forth a catastrophe that would forever change the country of Japan. In the years following the Sky Wall Disaster, the rising of the Sky Wall divided the country into three warring territories: Touto (Eastern Capital), Hokuto (Northern Capital) and Seito (Western Capital), and created a series of unidentified monsters known as Smash that relentlessly attack the public. To combat this chaos, the Touto government requested the help of Sento Kiryu, a genius and prodigious physicist to help decipher the mysteries left behind by both the Pandora Box and the Smash. Alongside prison escapee Ryuga Banjo, who was wrongfully framed for a murder he did not commit, the duo embark on a journey as Kamen Riders to uncover the mysteries surrounding the Pandora Box, the Smash, and their own pasts. Their journey would not come easy as they face adversaries from Hokuto and Seito, whom they must ultimately confide in if they are to have any hope in stopping their mutual enemy, Evolto from destroying the planet that they hold dear.
Similar to the previous series, half of each episode's title is an English word, though spelled in katakana instead of English letters, and the other is written in kanji, similar to the transformation announcements of most Best Match Forms. Most of the episodes contain formulas from mathematics or physics to form each episode number in the title cards.
Episode 1-16: Chapter One: This arc deals with Sento meeting Ryuga as he attempts to help him clear his name while collecting bottles from Smash created by Faust. The main antagonists of this arc are Blood Stalk and Night Rogue.
Episode 17-28: Chapter Two: This deals with Touto’s battle against the other two nations of Japan, Hokuto and Seito. It also features the debut of Grease, Rogue, the Hokuto Sanbagrasu, the Hell Bros, the Sclash Driver, and the Hazard Trigger.
Episode 29-49: Chapter Three: This deals with the rise of the Pandora Tower, the reveal of Evolto and his rider form, as well as the Riders uniting to save Earth from being destroyed by a black hole.
This series is the final Rider series to have a full televised run in the Heisei Era.
With this series, Kamen Rider's timeslot changes from 8am to 9am starting in October.
This series opening credits reuse the same font style that was used in Kamen Rider Ex-Aid.
In keeping with the science motif, a few of the equations, graphs, formula and matrix seen in the background or Rider's finisher in the show are based on math, scientific theories or scientific principles. These objects are provided by professors from Keio University, Kyushu University, Kyoto University and JSPS after a discussion of how to show characters' emotion symbolically.