|This article is about a/an kaijin in Kamen Rider Black.|
Buffalo Mutant was used by Gorgom in order to possess a girl named Mami so she can be good at sports like baseball and soccer as part of their plan to break the trust within humans. After Buffalo Mutant beat up one of the kids that mocked her, Buffalo Mutant started to concern her parents which is when Buffalo Mutant took action. In the form of a man, Buffalo Mutant told her that adults cannot be trusted. When it came out of Mami, Kohtaro became Kamen Rider Black and attacked (even when it repossessed Mami). It gave Kamen Rider Black a disadvantage with Mami possessed by it. In the second battle near a factory, Mami was able to get Buffalo Mutant out after stepping on a fallen electric wire. Kohtaro transforms into Kamen Rider Black and chopped off Buffalo Mutant's horns. Buffalo Mutant was killed by the Rider Kick.
Bufallo Mutan possesses a great deal of brute force and able to ram through things on ease like its animal base. Other than human-like sentience and even able to assume human disguise, Buffalo Mutant can also possess humans as it did to its target Mami.